Was the project wiped blank while you were working on it, or after opening it?
In general when users encounter issues like this with project frames wiping, we recommend going through this recovery guide, particularly the “Save File Verification” section to see if the images are still in your project files. It’s very strange that every project would be wiped, particularly if there are any projects you’ve opened and had working that have not been modified since.
First, make sure you are using the latest version of Pencil2D. In the top menu under Help > About, it should say version 0.7.0. If not, please upgrade as older versions were more prone to corrupting projects, especially wiping frames.
Second, verify that you have some free storage space on your computer. If you are really low on space on the drive that contains your temporary directory (on Windows: %TEMP%, usually the C: drive), all sorts of strange things can occur. Pencil2D needs at least the same amount of free space as the size of your project.
If you’ve got plenty of free space, then if you don’t mind please share here or send me privately one or more of your projects and I can try to open it myself to see if it as an issue with your computer or the project files.