I recently found an interesting method of creating effects animation in Toon Boom Harmony by creating empty frames creating a cycle of them in timeline. Then just draw straight ahead and keep adding stuff until you get a nice looping result.
This could easily be accomplished with Pencil 2D if you allow the loop playback button to loop frames when the user is flipping manually trough frames (alt/option+.)
This would be a nice little addition to Flip and Roll, which is very nice and something I haven’t seen in other packages.