@harihkh Hi. If you’re using the Windows operating system along your wacom drawing tablet, please check this guide / reply and the sub guides linked in it: Wacom intuos jagged lines windows 10
Take your time following the guide as thoroughly as you can, but once you’re done if you continue to have issues then we can try to troubleshoot Pencil2D.
Unfortunately the problem you’re describing seems to be a direct result of a Windows issue that occurs due to Microsoft changing how tablet drivers interact with the Windows OS.